Identifier: reportoffirstexp00harvuoft (find matches)
Title: Report of first expedition to South America, 1913. Members of the expedition: Richard P. Strong (and others)
Year: 1915 (1910s)
Authors: Harvard Medical School. Dept. of Tropical Medicine Strong, Richard Pearson, 1872-
Subjects: Medical geography -- South America Tropics -- Diseases and hygiene
Publisher: Cambridge Harvard University Press
Contributing Library: Gerstein - University of Toronto
Digitizing Sponsor: MSN

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<• <% Fig. 2 Showing endothelial phagocytes in sinusoids, enclosing erythrocytes, erythroblasts, polymorphonuclear leukocytes, and pigment. Plate XIV — Oroya Fever Liver
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ua J > oo > w <►J ca; c 5. U u C ao O a. T3 J3 •an c % o CO HISTOPATHOI.OGY 51 in pulp and much congested; many nucleated red blood-corpuscles are visible. Large swollen endothelial cells, some-times free, at others attached to the walls of the blood-vessels,and occasionally containing rounded and rod-shaped elementsare observed. Endothelial phagocytes freciuently contain-ing red blood-cells are also present in abundance. In thebone marrow there is also striking evidence of phagocytosisby endothelial leukocytes of the red corpuscles in variousstages of development, and of polymorphonuclear leukocytesas well as increased production of normoblasts. It seemsprobable that this extensive phagocytosis which is evident inthe liver, spleen, and bone marrow is also an indication of theaction of a toxic substance which has led to chemical changesor injury in the engulfed cells. In the lymijhatic glands the most striking pathological pic-ture which at once attracts the attention is

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